EVIDENCE FOR A ROLE OF GABA IN METABOLIC DEPRESSION DURING ANOXIA IN CRUCIAN CARP (CARASSIUS CARASSIUS)

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Effects of prolonged anoxia on electrical activity of the heart in crucian carp (Carassius carassius).

The effects of sustained anoxia on cardiac electrical excitability were examined in the anoxia-tolerant crucian carp (Carassius carassius). The electrocardiogram (ECG) and expression of excitation-contraction coupling genes were studied in fish acclimatised to normoxia in summer (+18°C) or winter (+2°C), and in winter fish after 1, 3 and 6 weeks of anoxia. Anoxia induced a sustained bradycardia...

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Thermal adaptation of the crucian carp ( Carassius carassius ) cardiac delayed

6 7 8 Minna Hassinen, Salla Laulaja, Vesa Paajanen, Jaakko Haverinen and Matti Vornanen 9 University of Eastern Finland, Department of Biology, P.O. Box 111, 80101 Joensuu, Finland 10 11 12 13 Short title: Thermal adaptation of cardiac potassium current in crucian carp 14 15 16 17 Address for correspondence: 18 Matti Vornanen 19 University of Eastern Finland 20 Department of Biology, P.O. box 1...

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Expression of heat shock proteins in anoxic crucian carp (Carassius carassius): support for cold as a preparatory cue for anoxia.

The crucian carp (Carassius carassius) tolerates anoxia for days to months depending on temperature. During episodes of stress, heat shock proteins (HSPs) are important for limiting cellular damage, mainly by ensuring protein function. Accordingly, we hypothesized that anoxia would change the expression of HSPs and that this response would be temperature dependent. Real-time RT-PCR was used to ...

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Seasonality of dihydropyridine receptor binding in the heart of an anoxia-tolerant vertebrate, the crucian carp (Carassius carassius L.).

Prolonged anoxia tolerance of facultative anaerobes is based on metabolic depression and thus on controlled reduction of energy-utilizing processes. One proposed survival mechanism is the closing of ion channels to decrease energetic cost of ion pumping (Hochachka PW. Science 231: 234-241, 1986). To test this hypothesis, the involvement of L-type Ca2+ channels in seasonal anoxia tolerance of th...

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Intrinsic contractile properties of the crucian carp (Carassius carassius) heart during anoxic and acidotic stress.

The crucian carp (Carassius carassius) seems unique among vertebrates in its ability to maintain cardiac performance during prolonged anoxia. We investigated whether this phenomenon arises in part from a myocardium tolerant to severe acidosis or because the anoxic crucian carp heart may not experience a severe extracellular acidosis due to the fish's ability to convert lactate to ethanol. Spont...

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ژورنال

عنوان ژورنال: Journal of Experimental Biology

سال: 1992

ISSN: 1477-9145,0022-0949

DOI: 10.1242/jeb.164.1.243